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  • 發布時間:2022-08-08 16:47 原文鏈接: 與白血病相關的AEBP1基因編碼功能描述

    這個基因編碼羧肽酶A蛋白家族的一個成員。編碼蛋白可能作為轉錄抑制因子發揮作用,并在脂肪生成和平滑肌細胞分化中發揮作用。對小鼠的研究表明,這種基因在傷口愈合和腹壁發育中起作用。該基因的過度表達與膠質母細胞瘤有關。
    This gene encodes a member of carboxypeptidase A protein family. The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that this gene functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma.

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