該基因編碼的蛋白質是富含絲氨酸/精氨酸(SR)的前mRNA剪接因子家族的一員,構成剪接體的一部分。這些因子中的每一個都包含一個結合RNA的RNA識別基序(rrm)和一個結合其他蛋白質的rs域。RS域富含絲氨酸和精氨酸殘基,促進不同SR剪接因子之間的相互作用。除了對mRNA剪接至關重要外,SR蛋白還被證明參與了從細胞核的mRNA輸出和翻譯。該基因有兩個編碼相同蛋白質的轉錄變體和一個非編碼轉錄變體。此外,在11號染色體上發現了該基因的一個假基因。
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11.