該基因編碼Swi/Snf家族的一個成員，其成員具有螺旋酶和ATP酶活性，并被認為通過改變這些基因周圍的染色質結構來調節某些基因的轉錄。編碼蛋白是大型ATP依賴染色質重塑復合物snf/swi的一部分，這是染色質抑制的基因轉錄激活所必需的。它至少有兩個保守域，對其功能可能很重要。首先，它有一個DNA結合域，可以特異性結合β-珠蛋白位點的snf/swi復合物所識別的富AT DNA序列。第二，蛋白的C端可刺激糖皮質激素受體依賴性轉錄激活。據認為，該基因編碼的蛋白質對snf/swi復合物具有特異性，并可能通過蛋白質DNA或蛋白質-蛋白質相互作用將該復合物招募到其靶點。兩個編碼不同亞型的轉錄變體已經被發現。
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene.