該基因編碼的蛋白質是胰蛋白酶抑制劑，由胰腺腺泡細胞分泌到胰液中。它被認為在防止胰蛋白酶催化的胰腺和胰管內酶原的過早激活方面起作用。該基因突變與遺傳性胰腺炎和熱帶鈣化性胰腺炎有關。[由RefSeq提供，2008年10月]
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008]