該基因編碼ras相關GTPase亞家族的一個成員。編碼蛋白參與調節與細胞應激相關的p38 mapk依賴性信號級聯。該蛋白還與神經生長因子協同促進神經元的發育和再生。交替剪接導致多個轉錄變體。
This gene encodes a member of a subfamily of Ras-related GTPases. The encoded protein is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants.