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  • 發布時間:2022-07-20 10:02 原文鏈接: 核受體信號通路相關因子LZTR1

    這個基因編碼一個btb-kelch超家族成員。最初被描述為一種基于與堿性亮氨酸拉鏈樣家族成員弱同源性的假定轉錄調節器,隨后編碼的蛋白質被證明僅局限于高爾基網絡,在那里它可能有助于穩定高爾基復合體。該基因缺失可能與Digeorge綜合征有關。
    This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome.

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