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  • 發布時間:2022-07-25 09:41 原文鏈接: ACOT13基因突變與藥物因子介紹

    這個基因編碼硫酯酶超家族的一個成員在人類中,這種蛋白質與微管共同定位,是維持細胞增殖所必需的同源小鼠蛋白形成同四聚體,與線粒體有關。小鼠蛋白具有中、長鏈酰基輔酶A硫酯酶的功能。已發現該基因編碼不同亞型的多個轉錄變體。[由RefSeq提供,2009年5月]
    This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2009]

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