該基因編碼ADAMTS（一種具有血小板反應蛋白基序的去整合素和金屬蛋白酶）蛋白家族的成員。家族成員共享幾個不同的蛋白質模塊，包括一個預肽區、一個金屬蛋白酶結構域、一個類去整合素結構域和一個1型血栓素（TS-1）基序這個家族的個別成員在c-末端ts-1基序的數目上不同，并且有些具有獨特的c-末端結構域。該基因編碼的酶含有8個ts-1基序。它可能在胎兒發育過程中的肺細胞中發揮作用，或通過其蛋白水解酶活性在腫瘤過程中發揮作用，或作為一種可能參與細胞粘附調節的分子發揮作用。[由RefSeq提供，2008年7月]
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion. [provided by RefSeq, Jul 2008]