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  • 發布時間:2022-07-25 11:07 原文鏈接: BTLA基因突變與藥物因子介紹

    這個基因編碼免疫球蛋白超家族的一個成員編碼的蛋白質包含一個免疫球蛋白(Ig)結構域,是一個受體,通過傳遞抑制信號來抑制免疫應答選擇性剪接導致多個轉錄變體這個基因的多態性與類風濕關節炎的風險增加有關[由RefSeq提供,2011年8月]
    This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011]

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