該基因編碼一種蛋白質，在細胞核和中心體的微管依賴性結合中發揮作用。小鼠體內一種類似的蛋白質在神經前體細胞核運動的特征性模式——核運動的相互作用和神經前體的自我更新中都起作用這種基因的突變被預測會導致神經源性缺陷選擇性剪接導致多個轉錄變體[由RefSeq提供，2009年10月]
This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]