該基因編碼一種自身免疫性腫瘤抗原，屬于腫瘤睪丸抗原的eso/lage家族。這種蛋白在包括黑色素瘤、乳腺癌、膀胱癌和前列腺癌在內的多種癌癥中表達。這種蛋白也在正常睪丸組織中表達。PMID:10399963中描述了該基因的另一種開放式閱讀框產品。這種被稱為駱駝的替代蛋白是一種腫瘤抗原，被黑色素瘤特異性細胞毒性T淋巴細胞識別。交替剪接導致多個轉錄變體。
This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants.