該基因編碼的細胞質外周膜蛋白在微絨毛中起蛋白酪氨酸激酶底物的作用。作為erm蛋白家族的一員，該蛋白作為質膜和肌動蛋白細胞骨架之間的中間產物。這種蛋白在細胞表面結構的粘附、遷移和組織中起著關鍵作用，并與多種人類癌癥有關。一個位于3號染色體上的假基因已經被鑒定為該基因。另外，這個基因的剪接變體也被描述過。[由RefSeq提供，2008年7月]
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]