該基因編碼的蛋白是成纖維細胞生長因子（fgf）家族的一員。fgf家族成員具有廣泛的有絲分裂和細胞存活活性，參與多種生物學過程，包括胚胎發育、細胞生長、形態發生、組織修復、腫瘤生長和侵襲等。這種生長因子缺乏存在于fgf家族大多數成員中的n-末端信號序列，但它含有已被證明作為核定位信號的堿基殘基簇。當轉染到哺乳動物細胞中時，這種蛋白質在細胞核中積累，但不分泌。這個基因的具體功能尚未確定。報道了兩種編碼不同亞型的選擇性剪接轉錄變體。[由RefSeq提供，2008年7月]
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]