該基因屬于轉錄因子的叉頭家族,具有獨特的叉頭結構域。該基因的特異功能尚未確定,但可能在肌源性生長和分化中發揮作用。該基因與pax3的易位與肺泡橫紋肌肉瘤有關。
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.