該基因編碼一種DNA解纏酶，該酶偏好部分解纏的3’-尾底物，也能以ATP依賴的方式解纏部分RNA/DNA和RNA/RNA雙工這種酶是異質核RNA結合蛋白的一個成員，也是Ras信號轉導途徑的一個組成部分它通過與SH3結構域結合，特異性地與Ras GTPase激活蛋白結合已經描述了該基因的幾個選擇性剪接的轉錄變體，但其中一些變體的全長性質尚未確定。[由RefSeq提供，2008年7月]
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]