GABA是哺乳動物腦中的主要抑制性神經遞質，它在GABA-a受體上起作用，GABA-a受體是配體門控氯離子通道。這些通道的氯離子傳導可以由與GABA A受體結合的苯二氮卓類藥物調節。已經鑒定出至少16個不同的GABA A受體亞基。另外，已經發現該基因編碼不同亞型的剪接轉錄變體[ RefSeq，2013月11日]
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]