該基因編碼一個與gmeb2蛋白相關的kdwk基因家族成員。gmeb1-gmeb2復合物是細小病毒dna復制的關鍵。在大鼠體內對類似基因的研究表明，該基因的作用是調節糖皮質激素受體與糖皮質激素反應元件結合時的反式激活。存在三種不同編碼亞型的剪接轉錄變體。[由RefSeq提供，2016年2月]
This gene encodes a member of KDWK gene family which associates with GMEB2 protein. The GMEB1-GMEB2 complex is essential for parvovirus DNA replication. Studies in rat for a similar gene suggest that this gene's role is to modulate the transactivation of the glucocorticoid receptor when it is bound to glucocorticoid response elements. Three alternative spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Feb 2016]