該基因編碼的蛋白質是一種含有5'-肌醇磷酸酶的sh2，參與調節胰島素功能。編碼蛋白在表皮生長因子受體轉換和肌動蛋白重塑的調控中也起著重要作用。此外，該基因支持乳腺癌的轉移生長，是乳腺癌的一個有價值的生物標志物。[由RefSeq提供，2009年1月]
The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer. [provided by RefSeq, Jan 2009]