該基因編碼絲氨酸/蘇氨酸蛋白激酶Par-1家族的一個成員該蛋白是上皮細胞和神經元細胞極性的重要調節因子，通過磷酸化和失活多種微管結合蛋白來調控微管的穩定性。蛋白質定位于細胞膜已發現該基因編碼不同亞型的多個轉錄變體。[由RefSeq提供，2009年7月]
This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]