該基因編碼的蛋白質包含四個kringle結構域和一個絲氨酸蛋白酶結構域，與在肝生長因子中發現的類似盡管存在絲氨酸蛋白酶結構域，編碼的蛋白質可能沒有任何蛋白水解活性。這種蛋白的受體是RON酪氨酸激酶，激活后可刺激纖毛上皮肺細胞的纖毛運動這種蛋白質被分泌和切割形成一個α鏈和一個由二硫鍵連接的β鏈。[由RefSeq提供，2010年1月]
The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds. [provided by RefSeq, Jan 2010]