該基因編碼的蛋白質是CRK相關底物家族的成員。這個家族的成員是粘附對接分子，它介導信號轉導途徑的蛋白質-蛋白質相互作用。這種蛋白是一種局灶性粘附蛋白，在細胞附著、遷移和侵襲以及細胞凋亡和細胞周期中起著重要的調控信號復合物的作用。這種蛋白也被報道在癌癥轉移中起作用。選擇性剪接導致多個轉錄變體。
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants.