這個位點編碼一個ATP依賴染色質重塑復合物的亞單位。編碼蛋白被鑒定為核激素受體激活配體依賴性轉錄所必需的復合物的組成部分。該位點的突變與原發性透明細胞腎細胞癌有關。
This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma.