該基因編碼內質網（er）蛋白中的一個二硫鍵異構酶（pdi）家族成員，該家族催化蛋白質折疊和硫醇二硫鍵交換反應。編碼的蛋白質具有N-端ER信號序列，兩個硫氧還蛋白（Trx）結構域，具有非經典Ser-Lys Gln SER和Ser-Lys Lys Cys基序，分別是兩個類Trx樣結構域和C-末端ER保留序列。該蛋白在體外缺乏氧化還原酶活性，可能作為伴侶。這個基因的表達似乎僅限于睪丸。
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has has an N-terminal ER-signal sequence, two thioredoxin (TRX) domains with non-classical Ser-Lys-Gln-Ser and Ser-Lys-Lys-Cys motifs, respectively, two TRX-like domains, and a C-terminal ER-retention sequence. The protein lacks oxidoreductase activity in vitro and probably functions as a chaperone. This gene's expression appears to be limited to the testis.