該基因編碼一種參與糖基磷脂酰肌醇(gpi)錨定生物合成的蛋白質。GPI錨定物是一種糖脂,在其核心骨架中含有三個甘露糖分子,在許多血細胞中被發現,用來將蛋白質錨定在細胞表面編碼蛋白和另一個gpi合成蛋白pigo在gpi中的乙醇胺磷酸轉移到第三個甘露糖中起作用。另外,還描述了編碼不同亞型的剪接轉錄變體。
This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described.