磷脂酰肌醇3激酶（pi3k）磷酸化磷脂酰肌醇和類似的化合物，然后作為第二信使的生長信號途徑。pi3k由一個催化亞基和一個調節亞基組成。該基因編碼的蛋白代表pi3k的一個調節亞單位，編碼的蛋白包含兩個sh2結構域，通過這兩個結構域結合活化的蛋白酪氨酸激酶來調節其活性。
Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity.