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  • 發布時間:2022-08-22 10:22 原文鏈接: PRKACB基因編碼的功能和結構描述

    這個基因編碼的蛋白質是絲氨酸/蘇氨酸蛋白激酶家族的成員編碼蛋白是環腺苷酸依賴性蛋白激酶的催化亞單位,通過環腺苷酸介導信號傳導。camp信號傳導對細胞增殖和分化等過程具有重要作用。已觀察到編碼不同亞型的多個選擇性剪接轉錄變體。

    The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. 

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