該基因編碼一種分泌的伴侶蛋白,可防止其他分泌蛋白的聚集,包括與神經退行性疾病和代謝性疾病相關的蛋白該編碼蛋白最為人所知的可能是其在前激素轉化酶PC2(由基因ID:5126編碼)的運輸和激活中的作用已證明編碼蛋白的磷酸化對其伴侶功能有抑制作用。該基因還產生一個ARHGAP11A-SCG5閱讀轉錄物和ARHGAP11A-SCG5蛋白[由RefSeq提供,2019年2月]
This gene encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins, including proteins that are associated with neurodegenerative and metabolic disease. The encoded protein may be best known for its role in the trafficking and activation of prohormone convertase PC2 (encoded by Gene ID: 5126). Phosphorylation of the encoded protein has been shown to have an inhibitory effect on its chaperone function. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein. [provided by RefSeq, Feb 2019]