該基因編碼細胞異質核核糖核蛋白(hnrnp)家族的一個成員。hnrnps是一種rna結合蛋白,它與異質核rna(hnrna)復合,調節rna的選擇性剪接、多聚腺苷酸化和其他方面的代謝和轉運。編碼蛋白在mrna成熟的多個方面發揮作用,并與多種多蛋白復合物(包括apob-rna編輯復合物和運動神經元存活復合物)相關。另外,該基因的剪接轉錄變體編碼多個亞型,并且該基因的假基因位于20號染色體的短臂上。
This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20.